Overview

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1 Original paper

The original pdf source of Lo et al. (2016) is embedded in Figure 1.

Figure 1

2 ODE model and network

We report in Figure 2 the biological network model underlying the intertwined interactions between immune cell subtypes (T-cells and Macrophaes) and realeased cytokines.

Figure 2: Bi-Directed diagram describing the interactions between immune cells in the inflammatory bowel disease IBD, from Lo et al. (2016), pp. 3

3 Reproducibility

The list of packages required for reproducing the tutorials are listed in Table 1:

##  Finding R package dependencies ... Done!

Source	Package
patient_stratification	CoRC
	cowplot
	dplyr
	flextable
	ggplot2
	latex2exp
	readr
	scales
	tidyr
	purrr
	tibble
prcc	CoRC
	dplyr
	flextable
	ggplot2
	lhs
	parallel
	ppcor
	tibble
	readr
	tidyr
steady_state	CoRC
	dplyr
	flextable
	testthat
2-IBD-simulations	CoRC
	dplyr
	flextable
	tidyr
	readr

Table 1: List of dependencies, per file.

References

Lo, Wing-Cheong, Violeta Arsenescu, Razvan I. Arsenescu, and Avner Friedman. 2016. “Inflammatory Bowel Disease: How Effective Is TNF-\(\alpha\) Suppression?” PloS One 11 (11): e0165782. https://doi.org/10.1371/journal.pone.0165782.